Asexual reproduction in animals and overview
Std 8–11 introduced human reproduction and cell division; here we study gametogenesis, the menstrual cycle, pregnancy and reproductive health in detail.
A small bud grows on a Hydra, separates and becomes a new Hydra.
Reproduction = forming new individuals like the parent. Asexual: one parent, no meiosis or gametes (clones). Sexual: formation and fusion of gametes (amphimixis).
In the figure : Asexual reproduction and overview of sexual reproduction.
Rule 1 : Gemmule, budding and regeneration — Gemmule: only in sponges (Spongilla); an internal mass of archaeocytes wrapped in a thick coat; survives bad times, hatches into a new sponge later. Budding: Hydra, corals, some ascidians; bud at base → tentacles → detaches. Regeneration: regrowing a lost part; not reproduction, but Planaria can also split into two clones.
- Easy : Gemmule = sponge.
- Medium : Budding = Hydra.
- Exam-type (CET) : Regeneration ≠ reproduction.
Rule 2 : Overview of sexual reproduction — Two phases: juvenile (growth; no breeding) and reproductive maturity. Events: pre-fertilization (gametogenesis, gamete transfer), fertilization, post-fertilization (zygote, embryogenesis). Seasonal breeders: goat, sheep; continuous breeders: humans, apes. Humans: gametogenesis → insemination → internal fertilization → zygote → gestation → parturition. Primary sex organs: testis, ovary; others = secondary. Secondary sexual characters (beard, breasts, voice) = sexual dimorphism.
- Easy : Primary = testis, ovary.
- Medium : Human = continuous breeder.
- Exam-type (CET) : Amphimixis = sexual mixing.
G-B-R: Gemmule (sponge), Budding (Hydra), Regeneration (Planaria).
‘Regeneration is reproduction’ is wrong. Trap: ‘gemmules occur in all animals’ is wrong (sponges only).
Memory clue : "Gemmule = a gem in a shell".
Spot the difference
| Method | Animal |
|---|---|
| Gemmule | Spongilla |
| Budding | Hydra, coral |
| Regeneration | Planaria |
Practice questions
- 1What is asexual reproduction?
- 2Where do gemmules occur?
- 3Gemmule is made of?
- 4Reproduction in Hydra?
- 5Example of continuous breeder?
- 6Primary sex organs?
- 7Example of secondary sexual character?
- 8What is amphimixis?
Show answers (try them yourself first)
- 1From one parent without gametes.
- 2In sponges.
- 3Archaeocytes.
- 4Budding.
- 5Humans, apes.
- 6Testis and ovary.
- 7Beard / breasts.
- 8Sexual reproduction.
Male reproductive system
A factory makes goods that travel through a pipeline gaining fluids on the way — just like sperm.
Male system: testes (primary), accessory ducts, accessory glands, external genitalia (penis, scrotum).
In the figure : Male reproductive system and duct path.
Rule 1 : Testes, scrotum and histology — Testes: mesodermal; descend into the scrotum via the inguinal canal; 4–5 cm; 200–300 lobules, each with 1–4 seminiferous tubules (germinal epithelium = spermatogonia + Sertoli cells: nutrition). Between tubules: Leydig (interstitial) cells: testosterone. Coverings: tunica albuginea, tunica vaginalis. The scrotum keeps 2–3 °C cooler (cremaster + dartos). Failure to descend = cryptorchidism (sterility); gubernaculum; inguinal hernia.
- Easy : Sertoli = nutrition; Leydig = testosterone.
- Medium : Scrotum = cooler.
- Exam-type (CET) : Testis must stay cool.
Rule 2 : Ducts, glands and semen — Ducts: seminiferous tubules → rete testis → vasa efferentia (12–20) → epididymis (sperm mature) → vas deferens → ejaculatory duct (joined by seminal vesicle) → urethra (urine + semen; urinogenital duct). Glands: seminal vesicles (~60%; alkaline; fructose, fibrinogen, prostaglandins), prostate (~30%; slightly acidic; citric acid, acid phosphatase), Cowper's (lubricant). Semen: 2.5–4 ml, ~400 million sperm, pH 7.2–7.7. Penis: 2 corpora cavernosa + 1 corpus spongiosum; glans; prepuce.
- Easy : Fructose = sperm energy.
- Medium : Seminal vesicle ≈ 60% of semen.
- Exam-type (CET) : Urethra = common passage.
S-R-V-E-V-E-U: Seminiferous, Rete, Vasa efferentia, Epididymis, Vas deferens, Ejaculatory duct, Urethra.
‘Sertoli cells make testosterone’ is wrong (Leydig). Trap: ‘prostate ~60%’ is wrong (30%).
Memory clue : "Leydig = lead hormone; Sertoli = sustains sperm".
Spot the difference
| Gland | % of semen | Key |
|---|---|---|
| Seminal vesicle | ~60% | Fructose |
| Prostate | ~30% | Citric acid |
| Cowper's | small | Lubricant |
Practice questions
- 1Role of seminiferous tubule?
- 2What do Leydig cells make?
- 3Role of Sertoli cells?
- 4Why is the scrotum cooler?
- 5Role of epididymis?
- 6What is cryptorchidism?
- 7Volume of semen?
- 8Role of Cowper's gland?
Show answers (try them yourself first)
- 1Sperm production.
- 2Testosterone.
- 3Nourish developing sperm.
- 4For spermatogenesis.
- 5Sperm maturation.
- 6Undescended testis.
- 72.5–4 ml.
- 8Lubrication.
Female reproductive system
The ovary is the egg store, the oviduct the passage, the uterus the baby's home.
Female system: ovaries (primary), oviducts, uterus, vagina, external genitalia, vestibular and mammary glands.
In the figure : Female reproductive system.
Rule 1 : Ovary and follicles — Ovary: 3 × 1.5 × 1 cm; central medulla + outer cortex (germinal epithelium; follicles). 5 hormones: estrogen, progesterone, relaxin, activin, inhibin. ~2 million primordial follicles in the foetus; ~1 million at birth; 60–80 thousand at puberty (atresia). Follicle: primordial → primary → secondary → tertiary → Graafian. Graafian: theca externa/interna, membrana granulosa, antrum (liquor folliculi), zona pellucida, corona radiata, cumulus oophorus. After ovulation corpus luteum → (no fertilization) corpus albicans. Menarche ~13 y; menopause 45–55; ~416 eggs.
- Easy : Theca interna = estrogen.
- Medium : Atresia = follicle loss.
- Exam-type (CET) : 32 years × 13 = 416.
Rule 2 : Oviduct, uterus, vagina, breast — Oviduct: infundibulum (fimbriae, ostium), ampulla (fertilization here), isthmus. Uterus: pear-shaped, 7.5 × 5 × 2.5 cm; fundus (implantation), body, cervix (~2.5 cm). Wall: perimetrium, myometrium, endometrium. Vagina: birth canal. External: mons pubis, labia, clitoris, hymen; vestibular (Bartholin's) glands. Mammary glands: lobes → alveoli → lactiferous ducts → nipple.
- Easy : Ampulla = fertilization.
- Medium : Fundus = implantation.
- Exam-type (CET) : Endometrium = inner lining.
Oviduct: I-A-I (Infundibulum, Ampulla, Isthmus); uterus: F-B-C.
‘Fertilization in the uterus’ is wrong (ampulla). Trap: ‘corpus albicans secretes hormones’ is wrong (corpus luteum).
Memory clue : "Ampulla = action place; fundus = fix the embryo".
Spot the difference
| Part | Role |
|---|---|
| Infundibulum | Catches the egg |
| Ampulla | Fertilization |
| Fundus | Implantation |
| Cervix | Neck of uterus |
Practice questions
- 1Two roles of ovary?
- 2What is atresia?
- 3Layers of Graafian follicle?
- 4Site of fertilization?
- 5Site of implantation?
- 6Corpus luteum gives?
- 7When is menarche?
- 8When is menopause?
Show answers (try them yourself first)
- 1Eggs + hormones.
- 2Degeneration of follicles.
- 3Theca, granulosa, zona pellucida…
- 4Ampulla.
- 5Fundus.
- 6Progesterone.
- 7~13 years.
- 845–55 years.
Menstrual cycle and gametogenesis
A monthly rhythm: prepare, release an egg mid-way, then shed the lining.
The menstrual cycle lasts ~28 days: menses → proliferative → ovulation → secretory. Gametogenesis = formation of sperm (spermatogenesis) and egg (oogenesis).
In the figure : 28-day cycle, spermatogenesis and oogenesis.
Menstrual cycle and gametogenesis
In the app you can move this figure with your finger.
Open in the appRule 1 : Menstrual cycle — Menses (days 1–5): endometrium is shed. Proliferative / follicular (5–13): FSH → follicles, estrogen → endometrium regrows. Ovulation (day 14): LH surge (positive feedback) → Graafian follicle ruptures releasing the secondary oocyte. Secretory / luteal (15–28; longest): corpus luteum → progesterone + estrogen + inhibin; endometrium 8–10 mm. If fertilized, hCG sustains the corpus luteum; if not, corpus albicans in 2 weeks and a new cycle.
- Easy : 5 + 9 + 14 = 28.
- Medium : LH surge = ovulation.
- Exam-type (CET) : Secretory = progesterone.
Rule 2 : Spermatogenesis and oogenesis — Spermatogenesis: multiplication (PGC → spermatogonia 2n, mitosis) → growth (primary spermatocyte 2n) → maturation (meiosis I → 2 secondary spermatocytes n → meiosis II → 4 spermatids) → spermiogenesis (acrosome, mitochondria in middle piece, tail). GnRH → FSH. Sperm: head (acrosome: hyaluronidase), neck (2 centrioles), middle piece (mitochondria), tail. Oogenesis: before birth oogonia → primary oocyte 2n, arrested in meiosis I; at puberty meiosis I completes → secondary oocyte + 1st polar body; the secondary oocyte arrests at metaphase II and is ovulated; meiosis II completes only on sperm entry → ovum + 2nd polar body. 1 oocyte → 1 ovum; 1 spermatocyte → 4 sperms.
- Easy : Oocyte: meiosis I starts before birth, arrests.
- Medium : Ovulated cell = secondary oocyte.
- Exam-type (CET) : 1 → 1 (female); 1 → 4 (male).
5-9-14 = 28: menses 5, proliferative 9, secretory 14. One egg, polar bodies discarded.
‘Primary oocyte is ovulated’ is wrong (secondary). Trap: ‘oogenesis starts at puberty’ is wrong (before birth).
Memory clue : "LH = Launch Hormone (launches the egg)".
Spot the difference
| Point | Sperm | Egg |
|---|---|---|
| Starts | puberty | before birth |
| Products | 1 → 4 | 1 → 1 + polar bodies |
| Hormone | FSH | FSH, LH |
Practice questions
- 1Length of the cycle?
- 2When is ovulation?
- 3What triggers ovulation?
- 4Longest phase?
- 5Role of hCG?
- 6Sperms from one primary spermatocyte?
- 7Role of acrosome?
- 8Cell that is ovulated?
Show answers (try them yourself first)
- 1~28.
- 2Day 14.
- 3LH surge.
- 4Secretory / luteal.
- 5Sustains corpus luteum.
- 64.
- 7Digests zona pellucida.
- 8Secondary oocyte (metaphase II).
Fertilization and early embryonic development
Millions of sperm race, but only one enters the egg and the door then shuts.
Fertilization = haploid sperm + egg → diploid zygote (in the ampulla). Then cleavage → morula → blastocyst → implantation → gastrulation.
In the figure : Steps of fertilization and early development.
Rule 1 : Mechanism of fertilization — ~50% of sperm are destroyed in the vagina; the rest undergo capacitation (5–6 h) and become hyperactive; prostaglandins and oxytocin help; speed 1.5–3 mm/min. Sperm live 24–48 h, the egg ~24 h. Acrosome reaction: hyaluronidase, zona lysin → penetrate corona radiata and zona pellucida; fertilizin–antifertilizin (species-specific). Cortical reaction: fertilization membrane → blocks polyspermy. The egg completes meiosis II → 2nd polar body; pronuclei fuse = syngamy (karyogamy) → zygote 2n; centrioles come from the sperm. Significance: diploid restored, sex fixed, variation.
- Easy : Capacitation = 5–6 h.
- Medium : Cortical reaction blocks polyspermy.
- Exam-type (CET) : Centrioles come from the sperm.
Rule 2 : Cleavage, implantation, gastrulation — Cleavage = repeated mitosis of the zygote (without growth) → blastomeres → morula → blastocyst (outer trophoblast + inner cell mass/embryoblast). The zona pellucida hides the sticky trophoblast until the uterus. Implantation ~day 7, in the fundus; syncytio- + cytotrophoblast; complete by day 10. Gastrulation: hypoblast (endoderm, yolk sac), epiblast (ectoderm, amnion); ~day 15 primitive streak → mesoderm → 3 layers. Ectoderm: skin, nervous system; mesoderm: muscle, blood, heart, kidney; endoderm: gut lining, liver, lungs.
- Easy : Cleavage = division without growth.
- Medium : Trophoblast outer; ICM inner.
- Exam-type (CET) : 3 layers: ecto-, meso-, endoderm.
Z-C-M-B-I-G: Zygote, Cleavage, Morula, Blastocyst, Implantation, Gastrula.
‘Cells grow during cleavage’ is wrong. Trap: ‘implantation in the ampulla’ is wrong (fundus).
Memory clue : "Trophoblast = sticks to the uterus; ICM = Inner Child Mass".
Spot the difference
| Layer | Forms |
|---|---|
| Ectoderm | Skin, brain |
| Mesoderm | Muscle, blood |
| Endoderm | Liver, lungs |
Practice questions
- 1What is capacitation?
- 2What does the acrosome release?
- 3How is polyspermy avoided?
- 4What is syngamy?
- 5What is a morula?
- 6Two parts of blastocyst?
- 7When does implantation begin?
- 8Mesoderm forms via?
Show answers (try them yourself first)
- 1Sperm becoming hyperactive.
- 2Hyaluronidase, zona lysin.
- 3Fertilization membrane.
- 4Fusion of pronuclei.
- 5Solid ball of cells.
- 6Trophoblast + inner cell mass.
- 7Day ~7.
- 8Primitive streak.
Pregnancy, placenta, parturition and lactation
For nine months mother and baby are linked by the placenta, a living bridge.
Gestation ~266 days (from fertilization) = 280 days (from LMP), 3 trimesters. Placenta = mother–foetus link. Parturition = birth; lactation = milk production.
In the figure : Trimesters, placenta and parturition.
Rule 1 : Trimesters and placenta — 1st (0–12 weeks): organogenesis; at 8 weeks a foetus (~3 cm); heartbeat by 6 weeks; morning sickness; high progesterone, periods stop. 2nd (13–26): rapid growth (~30 cm); hCG falls, corpus luteum regresses, the placenta makes progesterone. 3rd (27–birth): ~3–4 kg, 50 cm. Placenta: disc-shaped; foetal part = chorionic villi, plus a maternal part; supplies O₂, food, antibodies; removes CO₂, wastes; hormones hCG, HPL, estrogen, progesterone, relaxin. The only organ made of tissues from two individuals. Umbilical cord: 2 arteries (to placenta) + 1 vein. Amnion + amniotic fluid protect.
- Easy : 266 days from fertilization.
- Medium : Placenta = mother + foetus.
- Exam-type (CET) : Cord: 2 arteries + 1 vein.
Rule 2 : Parturition and lactation — Control: the mature foetus releases ACTH + corticoids → estrogen:progesterone ratio rises, oxytocin receptors increase → the mother's pituitary releases oxytocin → strong myometrial contractions (positive feedback). Three stages: dilation (cervix opens; amnion ruptures), expulsion (20–60 min; cord tied and cut), after-birth (placenta, 10–45 min). Lactation: prolactin makes milk; the first milk colostrum (yellow; proteins, lactose, IgA; low fat) gives the baby resistance.
- Easy : Oxytocin = labour contractions.
- Medium : Prolactin = milk.
- Exam-type (CET) : Colostrum = antibodies.
Oxytocin = Out (baby out); prolactin = production (milk).
‘Prolactin causes birth’ is wrong (oxytocin). Trap: ‘cord has 2 veins’ is wrong (2 arteries).
Memory clue : "2 arteries + 1 vein; colostrum = care-first milk".
Spot the difference
| Hormone | Source | Role |
|---|---|---|
| hCG | Placenta | Sustains corpus luteum |
| Oxytocin | Pituitary | Labour contractions |
| Prolactin | Pituitary | Milk production |
Practice questions
- 1Gestation period?
- 2When is heartbeat heard?
- 3Role of placenta?
- 4Vessels in cord?
- 5Placental hormones?
- 6Three stages of labour?
- 7What is colostrum?
- 8Hormone for lactation?
Show answers (try them yourself first)
- 1266 days from fertilization.
- 2At 6 weeks.
- 3Exchange + hormones.
- 42 arteries + 1 vein.
- 5hCG, HPL, estrogen, progesterone, relaxin.
- 6Dilation, expulsion, after-birth.
- 7First milk (with IgA).
- 8Prolactin.
Reproductive health, birth control, STDs and infertility
Family planning means choosing when to have a baby; it needs information and means.
Reproductive health (WHO) = total physical, emotional, behavioural and social wellbeing in reproduction. Contraceptives prevent fertilization. ART helps in infertility.
In the figure : Birth control, STDs and ART.
Rule 1 : Reproductive health and birth control — RCH programme: awareness, facilities, support; reducing infertility, infant (IMR) and maternal (MMR) mortality; sex education in schools; ban on amniocentesis for sex determination; marriageable age boy 21, girl 18. Temporary: natural/safe period, coitus interruptus, lactational amenorrhea (high failure); chemical (foam, jelly); barrier — condom (Nirodh) (also protects against STDs), diaphragm; IUDs (Lippes loop, Copper-T, hormonal); pills, Saheli. Permanent: vasectomy, tubectomy. MTP (Act of 1971): legal abortion under medical advice.
- Easy : Condom also stops STDs.
- Medium : Vasectomy male; tubectomy female.
- Exam-type (CET) : IUD sits in the uterus.
Rule 2 : STDs and infertility: ART — STDs: gonorrhoea, syphilis, genital herpes, chlamydiasis, hepatitis B, HIV/AIDS; safe habits, condoms, early treatment. Infertility: physical, congenital, infection, stress, drugs. ART: IVF–ET (fertilization in the lab → ‘test tube baby’), ZIFT (zygote into the fallopian tube), IUT (embryo with more than 8 blastomeres into the uterus), GIFT (gametes into the tube), ICSI (sperm injected into the egg), AI / IUI (semen into the vagina/uterus).
- Easy : ZIFT = tube; IUT = uterus.
- Medium : ICSI = directly into egg.
- Exam-type (CET) : HIV is an STD.
ZIFT = Zygote Into Fallopian Tube; IUT = Into Uterus; ICSI = Inject Sperm Into egg.
‘Safe period is foolproof’ is wrong (high failure). Trap: ‘vasectomy is female’ is wrong.
Memory clue : "Vasectomy = vas deferens (male); tubectomy = tubes (female)".
Spot the difference
| Method | Type |
|---|---|
| Condom | Barrier + STD protection |
| Cu-T | IUD |
| Vasectomy / Tubectomy | Permanent |
| IVF / ICSI | ART |
Practice questions
- 1What is reproductive health?
- 2Aim of RCH?
- 3What is Nirodh?
- 4Examples of IUD?
- 5What is vasectomy?
- 6What is IVF?
- 7What is ICSI?
- 8Example of an STD?
Show answers (try them yourself first)
- 1Total wellbeing in reproduction.
- 2Reduce IMR, MMR, infertility.
- 3Government condom.
- 4Lippes loop, Cu-T.
- 5Male sterilisation.
- 6Fertilization outside the body.
- 7Sperm injected into egg.
- 8Syphilis / HIV.
Quick revision of the whole lesson
| Concept | Key fact |
|---|---|
| Asexual | Gemmule, budding, regeneration |
| Male | Sertoli, Leydig; semen 60/30% |
| Female | Graafian follicle; ampulla = fertilization |
| Cycle | 5-9-14 = 28; ovulation day 14 |
| Fertilization | Zygote → blastocyst → gastrula |
| Pregnancy | 266 days; 3 trimesters |
| Health | RCH; IUD; ZIFT/IUT |
🎯 Most important points for the exam
- Gemmule, budding.
- Male system and semen.
- Ovary, Graafian follicle.
- Menstrual cycle; gametogenesis.
- Fertilization and cleavage.
- Placenta, parturition.
- Birth control, ART.
Understand the concept → draw the figure → memorise the key points → solve questions yourself.